JOURNAL PAPERS

  1. Karmakar, RS, Huang, JF, Chu, CP, Mai, MH, Chao, JI, Liao, YC, and Lu, YW (2024) Origami-inspired conductive paper-based folded pressure sensor with interconnection scaling at the crease for novel wearable applications. ACS Applied Materials & Interfaces, 16 (3) 4231–4241.
  2. Lin, YW, Lin, TT, Chen, CH, Wang, RH, Lin, YH, Tseng, TY, Zhuang, YJ, Tang, SY, Lin, YC, Pang, JY, Chakravarthy, RD, Lin, HC, Tzou, SC, Chao, JI* (2023) Enhancing efficacy of albumin-bound paclitaxel for human lung and colorectal cancers through autophagy receptor sequestosome 1 (SQSTM1)/p62-mediated nanodrug delivery and cancer therapy, ACS Nano, 17(19): 19033-19051.
  3. Wang, RH, Chang, CJ, Chen, CH, Liu, KK, Chao, JI* (2023) Osimertinib induces the opposite effect of proliferation and migration in the drug resistance of EGFR-T790M non-small cell lung cancer cells. Anti-Cancer Agents in Medicinal Chemistry, 23:11.
  4. Jiang, FY, Zhang, YZ, Tai, YH, Chou, CY, Hsieh, YC, Chang, YC, Huang, HC, Li, ZQ, Hsieh, YC, Chen, IJ, Huang, BC, Su, YC, Lin, WW, Lin, HS, Chao, JI, Yuan, SS, Wang, YM, Cheng, TL, Tzou, SC* (2023) A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis. Inflammation and Regeneration, 43:13
  5. Lin, YW, Raj, EN, Liu, KK, Su, HC, Chang, CJ, Hsu, TC, Cheng, PY, Wang, RH, Lai, YH, Chen, CH, Lin, YC, Chao, JI* (2023) Targeting EGFR and monitoring tumorigenesis of human lung cancer cells in vitro and in vivo using nanodiamond-conjugated specific EGFR antibody. Pharmaceutics, 15: 111.
  6. Lin, CI, Chen, ZC, Chen, CH, Chang, YH, Lee, TC, Tang, TT, Yu, TZ, Yang, CM, Tsai, MC, Huang, CC, Yang, TZ, Lin, CC, Wang, RH, Chiou, GY, Jong, YJ, Chao, JI* (2022) Co-inhibition of Aurora A and Haspin kinases enhances survivin blockage and p53 induction for mitotic catastrophe and apoptosis in human colorectal cancer. Biochemical Pharmacology, 206: 115289.
  7. Wang, SP, Hsu, YP, Chang, CJ, Chan, YC, Chen, CH, Wang, RH, Liu, KK, Pan, PY, Wu, YH, Yang, CM, Chen, C, Yang, JM, Liang, MC, Wong, KK and Chao, JI* (2021) A novel EGFR inhibitor suppresses survivin expression and tumor growth in human gefitinib-resistant EGFR-wild type and -T790M non-small cell lung cancer. Biochemical Pharmacology, 193:114792.
  8. Chen, YJ, Huang, YA, Ho, CT, Yang, JM, Chao, JI, Li, MC and Hwang, E* (2021) A nanodiamond-based surface topography down-regulates the microRNA miR6236 to enhance neuronal development and regeneration. ACS Applied Bio Materials, 4: 890-902.
  9. Lin, YW, Tsou, KL, Fay, CD, Liu, X, H.Y Chung, HY, Sharma, D, Jeiranikhameneh, A, Kuo, PH, Tzeng, CK, Wallace, GG, Wu, CY, Ker, MD, Chao, JI* and Cheng, YT* (2020) A microvalve cell printing technique using riboflavin photosensitizer for selective cell patterning onto a retinal chip. Bioprinting, 20: e00097.
  10. Raj, EN; Lin, YW, Chen, CH Liu, KK and Chao, JI* (2020) Selective autophagy pathway of nanoparticles and nanodrugs: Drug delivery and pathophysiological effects. Advanced Therapeutics, 3: 2000085.
  11. Chen, PH, Chang, KM, Tseng, WC, Chen, CH and Chao, JI* (2019) Invasiveness and surgical timing evaluation by clinical features of ground-glass opacity nodules in lung cancers. Thoracic Cancer, 10: 2133-2141.
  12. Liao, WS, Ho, Y, Lin, YW, Raj, EN, Liu, KK, Chen, C, Zhou, XZ, Lu, KP and Chao, JI* (2019) Targeting EGFR of triple-negative breast cancer enhances the therapeutic efficacy of paclitaxel- and cetuximab-conjugated nanodiamond nanocomposite. Acta Biomaterilia, 86: 395-405.
  13. Lin, YW, Raj, EN, Liao, WS, Lin, J,Liu, KK, Chen, TH, Cheng, HC, Wang, CC, Li, LY, Chen, C and Chao, JI* (2017) Co-delivery of paclitaxel and cetuximab by nanodiamond enhances mitotic catastrophe and tumor inhibition. Scientific Reports, 7: 9814.
  14. Boobalan, R, Liu, KK, Chao, JI*, and Chen, C* (2017) Synthesis and biological assay of erlotinib analogues and BSA-conjugated erlotinib analogue. Bioorganic & Medicinal Chemistry Letters, 27:1784-1788. 
  15. Liu, KK, Qiu, WR, Raj, EN, Liu, HF, Huang, HS, Lin, YW, Chang, CJ, Chen, TH, Chen, C, Chang, HC, Hwang, JK, and  Chao, JI* (2017) Ubiquitin-coated nanodiamonds bind to autophagy receptors for entry into the selective autophagy pathway. Autophagy, 13: 187-200.
  16. Wang, YJ, Larsson, M, Chiou, SH, Nicholls, SJ, Chao, JI, and Liu, DM* (2016) The use of polymer-based nanoparticles and nanostructured materials in treatment and diagnosis of cardiovascular diseases: Recent advances and emerging designs. Progress in Polymer Science, 57: 153-178.
  17. Chang, CW, Yu, YC, Hsieh, YH, Chen, PM, Chao, JI, Yao, CC, Hsiung, CN, Chu, HW, Shen, CY, Cheng, CW* (2016) MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition by repressing its target gene Slug in breast cancer. Oncotarget, 7: 16462-16478.
  18. Hsieh, YH, Liu, KK, Sulake, RS, Chao, JI*, and Chen, C* (2015) Microwave-assisted efficient conjugation of nanodiamond and paclitaxel. Bioorganic & Medicinal Chemistry Letters, 25: 2074-2077.
  19. Huang, YA, Kao, CW, Liu, KK, Huang, HS, Chiang, MH, Soo, CR, Chang, HC, Chiu, TZ*, Chao, JI*, and Hwang, E* (2014) The effect of fluorescent nanodiamonds on neuronal survival and morphogenesis. Scientific Reports, 4: 6919. 
  20. Yin, KH, Hsieh, YH, Sulake, RS, Wang, SP, Chao, JI*, and Chen, C* (2014) Optimization of the gefitinib analogues with potent anticancer activity. Bioorganic & Medicinal Chemistry Letters, 24: 5247-5250. 
  21. Vankayala, R, Chiang, CS, Chao, JI, Yuan, CJ, Lin, SY, Hwang, KC (2014) A general strategy to achieve ultra-high gene transfection efficiency using lipid-nanoparticle composites. Biomaterials, 35: 8261-8272. 
  22. Lai, YJ, Lin, CI, Wang, CL, and Chao, JI* (2014) Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells. Journal of Cellular Biochemistry, 115:1888-1899. 
  23. Huang YT, Lin, CI, Chien, PH, Tang, TT, Lin, J and Chao, JI* (2014) The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer. Chemico-Biological Interactions, 220: 41-50. 
  24. Hsu, TC, Liu, KK, Chang, HC, Hwang, E, and Chao, JI* (2014) Labeling of neuronal differentiation and neuron cells using fluorescent nanodiamonds. Scientific Reports, 4: 5004. 
  25. Yang, CR, Liao, WS, Wu, YH, Murugan , K, Chen, C*, and Chao, JI* (2013) CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction. Toxicology and Applied Pharmacology, 273: 611-622.
  26. Yu, SY, Liu, HF, Wang, SP,Chang, CC, Tsai, CM, and Chao, JI* (2013) Evidence of securin-mediated resistance of gefitinib-induced apoptosis in human cancer cells. Chemico-Biological Interactions, 203:412-422.
  27. Vaijayanthimala,, Cheng, P, Yeh, SH, Liu, KK, Hsiao, CH*, Chao, JI*, and Chang, HC* (2012) The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo imaging contrast agent. Biomaterials, 33: 7794-7802. (Times Cited 210+)
  28. Lien, ZY, Hsu, TC, Liu, KK, Liao, WS, Hwang, KC, and Chao, JI* (2012) Cancer cell labeling and tracking using fluorescent and magnetic nanodiamond. Biomaterials, 33:6172-6185. 
  29. Cheng, CW*, Wang, HW, Chang, CW, Chu, HW, Chen, CY, Yu, JC, Chao, JI, Liu, HF, Ding, SL, and Shen, CY (2012) MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. Breast Cancer Research and Treatment, 134: 1081-93. (Times Cited 220+)
  30. Wang, G, Gao, Y, Li, L, Jin, G, Zhen C, Chao, JI, Lin, HK* (2012) K63-linked ubiquitination in kinase activation and cancer. Frontiers in Oncology, 2: 1-13.
  31. Tsai, CC, Liu, HF, Hsu, KC, Yang, JM, Chen, C, Liu, KK, Hsu, TS, and Chao, JI* (2011) 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration. Biochemical Pharmacology, 81: 856-865. 
  32. Liu, HF, Hu, HC, and Chao, JI* (2010) Oxaliplatin down-regulates survivin by p38 MAP kinase and proteasome in human colon cancer cells. Chemico-Biological Interactions, 188: 535-545. 
  33. Liu, KK, Zheng WW, Wang CC, Chiu, YC, Cheng, CL, Lo YS, Chen, C, and Chao, JI* (2010) Covalent linkage of nanodiamond-paclitaxel for drug delivery and cancer therapy. Nanotechnology, 21: 315106#. (#Selected for Journal Highlight paper and reported by Nanotechweb.org)(Times Cited 220+)
  34. Jiang, RH, Su, WC, Liu, HF, Huang, HS, and Chao, JI* (2010) Opposite expression of securin and gamma-H2AX regulates baicalein-induced cancer cell death. Journal of Cellular Biochemistry, 111: 274-283. 
  35. Liu, KK, Wang, CC, Cheng, CL and Chao, JI* (2009) Endocytic carboxylated nanodiamond for the labeling and tracking of cell division and differentiation in cancer and stem cells. Biomaterials, 30: 4249-4259. (Times Cited 200+)
  36. Liu, HF, Hsiao, PW, and Chao, JI* (2008) Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells. Chemico-Biological Interactions, 176: 48-57.
  37. Hsu, TS, Chen, C, Lee PT, Chiu, SJ, Liu, HF, and Chao, JI* (2008) 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound  induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway. Cancer Chemotherapy and Pharmacology, 62: 799-808. 
  38. Chang, CC*, Chen, PH, Chu, HL, Lee, TC, Chou, CC, Chao, JI, Su, JY, Chen, JS, Tsai, JS, Ho, YP, Sun, KW, and Cheng, CL (2008) Laser induced popcorn-like conformational transition of nanodiamond as a nano-knife. Applied Physics Letters, 93: 3395.
  39. Chiu, SJ*, Chao, JI, Lin, YJ, and Hsu, TS (2008) Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase -dependent pathway in human colorectal cancer cells. Toxicology Letters, 179: 63-70. 
  40. Liu, KK, Chen, MF, Chen, BI, Lee, TJF, Cheng, CL, Chang, CC, Ho, YP, and Chao, JI* (2008) Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond. Nanotechnology, 19: 205102. 
  41. Chiu, SJ, Hsu, TS, and Chao, JI* (2007) Expression of securin promotes colorectal cancer cell death via a p53-independent pathway after radiation. Chemico-Biological Interactions, 170: 153–161. 
  42. Chao, JI*, Su, WC, and Liu, HF (2007) Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT. Molecular Cancer Therapeutics, 6: 3039-3048. (Times Cited 160+)
  43. Chao, JI, Perevedentseva, E, Chung, PH, Liu, KK, Cheng, CY, Chang, CC, and Cheng, CL* (2007) Nanometer-sized diamond particle as a probe for biolabeling. Biophysical Journal, 93: 2199-2208#. (#Selected for the cover picture)(#Selected for the Virtual Journal of Nanotechnology Environment, Health and Safety, 2007) (Times Cited 290+)
  44. Hsiao, PW, Chang, CC, Liu, HF, Tsai, CM, Chiu, TH, and Chao, JI* (2007) Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells. Toxicology and Applied Pharmacology, 222: 97-104.
  45. Liu, KK, Cheng, CL, Chang, CC and Chao, JI* (2007) Biocompatible and detectable carboxylated nanodiamond on human cell. Nanotechnology, 18: 325102#. (#Selected for the Virtual Journal of Nanotechnology Environment, Health and Safety, 2007)(#Reported by the Nanotechnology Web of Nanowerk) (Times Cited 310+)
  46. Cheng, CY, Perevedentseva, E, Tu, JS, Chung, PH, Cheng, CL*, Liu, KK, Chao, JI*, Chen, PH, Chang, CC* (2007) Direct and in vitro observation of growth hormone receptor molecules in A549 human lung epithelial cells by nanodiamond labeling. Applied Physics Letters 90: 163903#. (#Selected for the Virtual Journal of Biological Physics Research) (Times cited 130+)
  47. Chiu, SJ, Hsu, TS, and Chao, JI* (2006) Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells. Toxicology Letters 167:122-130. 
  48. Chao, JI*, Hsu, SH, and Tsou, TC (2006) Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway. Toxicological Sciences 90: 73-86. 
  49. Chao, JI* and Liu, HF (2006) The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells. Molecular Pharmacology 69: 154-164. 
  50. Hsu, SH, Tsou, TC, Chiu, SJ, and Chao, JI* (2005) Inhibition of α7-nicotinic acetylcholine receptor expression by arsenite in the vascular endothelial cells. Toxicology Letters 159: 47-59. 
  51. Lin, J, Hsiao, PW, Chiu, TH, and Chao, JI* (2005) Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the cell death and growth inhibition in human colon cancer cells. Biochemical Pharmacology 70: 658–667.
  52. Kuo, PC, Liu, HF, and Chao, JI* (2004) Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells. Journal of Biological Chemistry 279: 55875-55885. (Times Cited 180+)
  53. Chao, JI*, Kuo, PC, and Hsu TS (2004) Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells. Journal of Biological Chemistry 279: 20267-20276. (Times cited 130+)

BOOK CHAPTER

  1. Chao, JI, Perevedentseva, E, Chang, CC, Cheng, CY, Liu, KK, Chung, PH, Tu, JS, Chu, CD, Cai, SJ, Cheng, CL (2010) Protein-nanodiamond complexes for cellular surgery, in nanodiamond and its bio applications using the spectroscopic properties as probe for bio-labeling. Nanodiamonds: Applications in Biology and Nanoscale Medicine, Springer, Chapter 9: 189-224.

PATENTS

  1. Chao,JI, Liu, KK, and Chen, CP. Quinazolinamine derivatives and pharmaceutical compositions and uses thereof (Taiwan Patent Number: I660728; Patent Permission Date: 2019/04/12; Valid Dates: 2019/06/01-2038/02/08)
  2. Chao,JI, Liu, KK, and Chen, CP. 4-anilinoquinazoline derivative and albumin conjugates thereof (US Patent Number: US10251886 B1; Patent Permission Date: 2018/12/21; Valid Dates: 2019/4/9-2038/02/23)
  3. Chao,JI, Liu, KK, and Hsu, YP. Method for overcoming drug resistance of EGFR mutation an cancerous stemness of human non-small cell lung carcinoma (US Patent number: US9980967 B1; Patent Permission Date: 2018/04/05; Valid Dates: 2018/05/09-2037/03/16)
  4. Chao,JI, Lien, ZY, and Hwang, KC. Separation method of labeled cells and uses thereof (Taiwan Patent Number: I5888258; Valid Dates: 2017/06/21~2031/11/16)
  5. Chao,JI, Lien, ZY, and Hwang, KC. Separation method of labeled cells and uses thereof (US Patent Application No. 13/471768; US Publication No. US 20130130236 A1).
  6. Chao, JI, Wang, SP, Chen, C, Yin, KH, Yang, JM, and Wu, YH. A compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof (People Republic of China Patent number: 2795573; Valid Dates: 2018/01/26~2034/09/22)
  7. Chao, JI, Wang, SP, Chen, C, Yin, KH, Yang, JM, Wu, YH. A compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof (Taiwan Patent Number: I567063; Valid Dates: 2017/01/21~2034/09/04)
  8. Chao, JI, Wang, SP, Chen, C, Yin, KH, Yang, JM, and Wu, YH. A compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof (US Patent Number: US9512086 B2; Valid Dates: 2016/12/6-2035/1/14)
  9. Chao,JI, Yang, CR, and Chen, CP. A vitamin K3 derivative for promoting apoptosis: A pharmaceutical composition containing the same and a use thereof (Taiwan Patent Number: I543759; Valid Dates: 2016/08/01~2034/03/10)
  10. Yang, JM, Hsu, KC, Hwang, E, Chen, WL, Hwang, WJ, and Chao, JI. A specific inhibitor for epidermal growth factor Receptor, a pharmaceutical composition and an use thereof (Taiwan Patent Number: I536987; Valid Dates: 2016/06/11~2033/12/26)
  11. Chao, JI, Cheng, CL, and Chen, C. Medicine and carrier comprising nanodiamond, method for preparing the same and use thereof (Taiwan Patent Number: I414309; Valid Dates: 2013/11/11~2029/07/12)
  12. Chao, JI, Cheng, CL, and Chen, C. Medicine and carrier comprising nanodiamond, method for preparing the same and use thereof (US Patent Application No. US 12/574958; US Publication No. US 2011/0008447 A1)
  13. Chao, JI, Hsu, TS, Chen, C, Lee PT, and Chiu, SJ. Compound capable of cytoskeleton and induction of cell elongation and process for synthesizing the same (Taiwan Patent Number: I359018; Valid Dates: 2012/03/01~2026/07/13).
  14. Chao, JI, Hsu, TS, Chen, C, Lee PT, and Chiu, SJ. Compound capable of cytoskeleton and induction of cell elongation and process for synthesizing the same (US Patent Publication No. US 2008/0015221 A1)