{"id":43,"date":"2020-07-01T13:28:38","date_gmt":"2020-07-01T05:28:38","guid":{"rendered":"https:\/\/anticancer.lab.nycu.edu.tw\/?page_id=43"},"modified":"2026-03-11T23:21:23","modified_gmt":"2026-03-11T15:21:23","slug":"courses","status":"publish","type":"page","link":"https:\/\/anticancer.lab.nycu.edu.tw\/index.php\/courses\/","title":{"rendered":"Publications"},"content":{"rendered":"\n

JOURNAL PAPERS<\/strong><\/h4>\n\n\n\n
  1. Lin, YC, Lin, YW, Wang, RH, Chang, CJ, Pang, JY, Hsiao, MC, Wang, HM, Wu, SY, Chiang, CM, and Chao, JI* (2026<\/strong>) SQSTM1\/p62-mediated PD-L1 biomolecular condensate formation promotes lung tumorigenesis. Journal of Advanced Research<\/strong>, in press<\/em><\/li>
  2. Karmakar, RS, Lin, HF, Huang, CC, Huang, JF, Chao, JI, Hsueh, CH, Liao, YC, Lu, YW* (2026<\/strong>) Stabilizing electrical contact resistance in flexible tactile sensors using Ag-Cu\/PEG hybrid composites. Sensors & Actuators: A. Physical<\/em> <\/strong>399, 117460.<\/li>
  3. Lin, YS, Chang, HY, Hong, WZ, Chen, JY, Huang, WC, Yuan, TT, Ke, TW, Tsai, YY, Chen, TH, Ji-An Liang, JA, Chao, JI, Chao, KS, Huang, CY* (2026<\/strong>)Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy. Cell Death & Disease<\/strong>,<\/em> 17(1):194.<\/li>
  4. Karmakar, RS, Lin, HF, Huang, JF, Chao, JI, Liao, YC, Lu, YW* (2025<\/strong>) A multi-layered origami tactile sensory ring for wearable biomechanical monitoring. Biosensors<\/strong>, <\/em>15(1), 8.<\/li>
  5. Karmakar, RS, Huang, JF, Chu, CP, Mai, MH, Chao, JI, Liao, YC, and Lu, YW (2024<\/strong>) Origami-inspired conductive paper-based folded pressure sensor with interconnection scaling at the crease for novel wearable applications. ACS Applied Materials & Interfaces, <\/em><\/strong>16 (3) 4231\u20134241.<\/li>
  6. Lin, YW, Lin, TT, Chen, CH, Wang, RH, Lin, YH, Tseng, TY, Zhuang, YJ, Tang, SY, Lin, YC, Pang, JY, Chakravarthy, RD, Lin, HC, Tzou, SC, Chao, JI* <\/sup>(2023<\/strong>) Enhancing efficacy of albumin-bound paclitaxel for human lung and colorectal cancers through autophagy receptor sequestosome 1 (SQSTM1)\/p62-mediated nanodrug delivery and cancer therapy, ACS Nano<\/em><\/strong>, 17(19): 19033-19051.<\/li>
  7. Wang, RH, Chang, CJ, Chen, CH, Liu, KK, Chao, JI* (2023<\/strong>) Osimertinib induces the opposite effect of proliferation and migration in the drug resistance of EGFR-T790M non-small cell lung cancer cells. Anti-Cancer Agents in Medicinal Chemistry<\/em><\/strong>, 23:11.<\/li>
  8. Jiang, FY, Zhang, YZ, Tai, YH, Chou, CY, Hsieh, YC, Chang, YC, Huang, HC, Li, ZQ, Hsieh, YC, Chen, IJ, Huang, BC, Su, YC, Lin, WW, Lin, HS, Chao, JI, Yuan, SS, Wang, YM, Cheng, TL, Tzou, SC* (2023<\/strong>) A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis. Inflammation and Regeneration<\/em><\/strong>, 43:13<\/li>
  9. Lin, YW, Raj, EN, Liu, KK, Su, HC, Chang, CJ, Hsu, TC, Cheng, PY, Wang, RH, Lai, YH, Chen, CH, Lin, YC, Chao, JI* (2023<\/strong>) Targeting EGFR and monitoring tumorigenesis of human lung cancer cells in vitro<\/em> and in vivo<\/em> using nanodiamond-conjugated specific EGFR antibody. Pharmaceutics<\/em><\/strong>,<\/em> 15: 111.<\/li>
  10. Lin, CI, Chen, ZC, Chen, CH, Chang, YH, Lee, TC, Tang, TT, Yu, TZ, Yang, CM, Tsai, MC, Huang, CC, Yang, TZ, Lin, CC, Wang, RH, Chiou, GY, Jong, YJ, Chao, JI* (2022<\/strong>) Co-inhibition of Aurora A and Haspin kinases enhances survivin blockage and p53 induction for mitotic catastrophe and apoptosis in human colorectal cancer. Biochemical Pharmacology<\/em><\/strong>, <\/em>206: 115289.<\/li>
  11. Wang, SP, Hsu, YP, Chang, CJ, Chan, YC, Chen, CH, Wang, RH, Liu, KK, Pan, PY, Wu, YH, Yang, CM, Chen, C, Yang, JM, Liang, MC, Wong, KK and Chao, JI* (2021<\/strong>) A novel EGFR inhibitor suppresses survivin expression and tumor growth in human gefitinib-resistant EGFR-wild type and -T790M non-small cell lung cancer. Biochemical Pharmacology, <\/em><\/strong>193:114792.<\/li>
  12. Chen, YJ, Huang, YA, Ho, CT, Yang, JM, Chao, JI, Li, MC and Hwang, E* (2021<\/strong>) A nanodiamond-based surface topography down-regulates the microRNA miR6236 to enhance neuronal development and regeneration. ACS Applied Bio Materials<\/em><\/strong>, <\/em>4: 890-902.<\/li>
  13. Lin, YW, Tsou, KL, Fay, CD, Liu, X, H.Y Chung, HY, Sharma, D, Jeiranikhameneh, A, Kuo, PH, Tzeng, CK, Wallace, GG, Wu, CY, Ker, MD, Chao, JI* and Cheng, YT* (2020<\/strong>) A microvalve cell printing technique using riboflavin photosensitizer for selective cell patterning onto a retinal chip. Bioprinting<\/strong>, <\/em>20: e00097.<\/li>
  14. Raj, EN; Lin, YW, Chen, CH Liu, KK and Chao, JI* (2020<\/strong>) Selective autophagy pathway of nanoparticles and nanodrugs: Drug delivery and pathophysiological effects. Advanced Therapeutics<\/strong>, <\/em>3: 2000085.<\/li>
  15. Chen, PH, Chang, KM, Tseng, WC, Chen, CH and Chao, JI* (2019<\/strong>) Invasiveness and surgical timing evaluation by clinical features of ground-glass opacity nodules in lung cancers. Thoracic Cancer<\/em>,<\/strong> 10: 2133-2141.<\/li>
  16. Liao, WS, Ho, Y, Lin, YW, Raj, EN, Liu, KK, Chen, C, Zhou, XZ, Lu, KP and Chao, JI*\u00a0(2019<\/strong>) Targeting EGFR of triple-negative breast cancer enhances the therapeutic efficacy of paclitaxel- and cetuximab-conjugated nanodiamond nanocomposite.\u00a0Acta Biomaterilia<\/em><\/strong>, 86: 395-405.<\/li>
  17. Lin, YW, Raj, EN, Liao, WS, Lin, J,Liu, KK, Chen, TH, Cheng, HC, Wang, CC, Li, LY, Chen, C and Chao, JI* (2017<\/strong>) Co-delivery of paclitaxel and cetuximab by nanodiamond enhances mitotic catastrophe and tumor inhibition.\u00a0Scientific Reports<\/em><\/strong>, 7: 9814.<\/li>
  18. Boobalan, R, Liu, KK, Chao, JI*, and Chen, C*\u00a0(2017<\/strong>) Synthesis and biological assay of erlotinib analogues and BSA-conjugated erlotinib analogue.\u00a0Bioorganic & Medicinal Chemistry Letters<\/em><\/strong>, 27:1784-1788.\u00a0<\/li>
  19. Liu, KK, Qiu, WR,\u00a0Raj, EN, Liu, HF, Huang, HS, Lin, YW, Chang, CJ, Chen, TH, Chen, C, Chang, HC,\u00a0Hwang, JK,\u00a0and\u00a0\u00a0Chao, JI*\u00a0(2017<\/strong>)\u00a0Ubiquitin-coated nanodiamonds bind to autophagy receptors\u00a0for entry into the selective autophagy pathway.\u00a0Autophagy<\/em><\/strong>, 13: 187-200.<\/li>
  20. Wang, YJ, Larsson, M, Chiou, SH, Nicholls, SJ, Chao, JI, and Liu, DM* (2016<\/strong>)\u00a0The use of polymer-based nanoparticles and nanostructured materials in treatment and diagnosis of cardiovascular diseases: Recent advances and emerging designs.\u00a0Progress in Polymer Science<\/em><\/strong>, 57: 153-178.<\/li>
  21. Chang, CW, Yu, YC, Hsieh, YH, Chen, PM, Chao, JI, Yao, CC, Hsiung, CN, Chu, HW, Shen, CY, Cheng, CW* (2016<\/strong>) MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition by repressing its target gene Slug in breast cancer. Oncotarget<\/strong><\/em>, 7: 16462-16478.<\/li>
  22. Hsieh, YH, Liu, KK, Sulake, RS, Chao, JI*, and Chen, C* (2015<\/strong>) Microwave-assisted efficient conjugation of nanodiamond and paclitaxel.\u00a0Bioorganic & Medicinal Chemistry Letters<\/em><\/strong>, 25: 2074-2077.<\/li>
  23. Huang, YA, Kao, CW, Liu, KK, Huang, HS, Chiang, MH, Soo, CR, Chang, HC, Chiu, TZ*, Chao, JI*, and Hwang, E* (2014<\/strong>) The effect of fluorescent nanodiamonds on neuronal survival and morphogenesis.\u00a0Scientific Reports<\/em><\/strong>, 4: 6919.\u00a0<\/li>
  24. Yin, KH, Hsieh, YH, Sulake, RS, Wang, SP, Chao, JI*, and Chen, C* (2014<\/strong>) Optimization of the gefitinib analogues with potent anticancer activity.\u00a0Bioorganic & Medicinal Chemistry Letters<\/em><\/strong>, 24: 5247-5250.\u00a0<\/li>
  25. Vankayala, R, Chiang, CS, Chao, JI, Yuan, CJ, Lin, SY, Hwang, KC (2014<\/strong>) A general strategy to achieve ultra-high gene transfection efficiency using lipid-nanoparticle composites.\u00a0Biomaterials<\/em><\/strong>, 35: 8261-8272.\u00a0<\/li>
  26. Lai, YJ, Lin, CI, Wang, CL, and Chao, JI* (2014<\/strong>) Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells.\u00a0Journal of Cellular Biochemistry<\/em><\/strong>, 115:1888-1899.\u00a0<\/li>
  27. Huang YT, Lin, CI, Chien, PH, Tang, TT, Lin, J and Chao, JI* (2014<\/strong>) The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer.\u00a0Chemico-Biological Interactions<\/em><\/strong>, 220: 41-50.\u00a0<\/li>
  28. Hsu, TC, Liu, KK, Chang, HC, Hwang, E, and Chao, JI* (2014<\/strong>) Labeling of neuronal differentiation and neuron cells using fluorescent nanodiamonds.\u00a0Scientific Reports<\/em><\/strong>, 4: 5004.\u00a0<\/li>
  29. Yang, CR, Liao, WS, Wu, YH, Murugan , K, Chen, C*, and Chao, JI* (2013<\/strong>) CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction.\u00a0Toxicology and Applied Pharmacology<\/em><\/strong>, 273: 611-622.<\/li>
  30. Yu, SY, Liu, HF, Wang, SP,Chang, CC, Tsai, CM, and Chao, JI* (2013<\/strong>) Evidence of securin-mediated resistance of gefitinib-induced apoptosis in human cancer cells.\u00a0Chemico-Biological Interactions<\/em><\/strong>, 203:412-422.<\/li>
  31. Vaijayanthimala,, Cheng, P, Yeh, SH, Liu, KK, Hsiao, CH*, Chao, JI*, and Chang, HC* (2012<\/strong>) The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo imaging contrast agent.\u00a0Biomaterials<\/em><\/strong>, 33: 7794-7802.\u00a0(Times Cited<\/a>\u00a0210+)<\/li>
  32. Lien, ZY, Hsu, TC, Liu, KK, Liao, WS, Hwang, KC, and Chao, JI* (2012<\/strong>) Cancer cell labeling and tracking using fluorescent and magnetic nanodiamond.\u00a0Biomaterials<\/em><\/strong>, 33:6172-6185.\u00a0<\/li>
  33. Cheng, CW*, Wang, HW, Chang, CW, Chu, HW, Chen, CY, Yu, JC, Chao, JI, Liu, HF, Ding, SL, and Shen, CY (2012<\/strong>) MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer.\u00a0Breast Cancer Research and Treatment<\/em><\/strong>, 134: 1081-93.\u00a0(Times Cited<\/a>\u00a0220+)<\/li>
  34. Wang, G, Gao, Y, Li, L, Jin, G, Zhen C, Chao, JI, Lin, HK* (2012<\/strong>) K63-linked ubiquitination in kinase activation and cancer.\u00a0Frontiers in Oncology<\/em><\/em><\/strong>, 2: 1-13.<\/li>
  35. Tsai, CC, Liu, HF, Hsu, KC, Yang, JM, Chen, C, Liu, KK, Hsu, TS, and Chao, JI* (2011<\/strong>) 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration.\u00a0Biochemical Pharmacology<\/em><\/strong>, 81: 856-865.\u00a0<\/li>
  36. Liu, HF, Hu, HC, and Chao, JI* (2010<\/strong>) Oxaliplatin down-regulates survivin by p38 MAP kinase and proteasome in human colon cancer cells.\u00a0Chemico-Biological Interactions<\/em><\/strong>, 188: 535-545.\u00a0<\/li>
  37. Liu, KK, Zheng WW, Wang CC, Chiu, YC, Cheng, CL, Lo YS, Chen, C, and Chao, JI* (2010<\/strong>) Covalent linkage of nanodiamond-paclitaxel for drug delivery and cancer therapy.\u00a0Nanotechnology<\/em><\/strong>, 21: 315106#<\/sup>. (#<\/sup>Selected for Journal Highlight paper and reported by Nanotechweb.org)(Times Cited<\/a>\u00a0220+)<\/li>
  38. Jiang, RH, Su, WC, Liu, HF, Huang, HS, and Chao, JI* (2010<\/strong>) Opposite expression of securin and gamma-H2AX regulates baicalein-induced cancer cell death.\u00a0Journal of Cellular Biochemistry<\/em><\/strong>, 111: 274-283.\u00a0<\/li>
  39. Liu, KK, Wang, CC, Cheng, CL and Chao, JI* (2009<\/strong>) Endocytic carboxylated nanodiamond for the labeling and tracking of cell division and differentiation in cancer and stem cells.\u00a0Biomaterials<\/em><\/strong>, 30: 4249-4259.\u00a0(Times Cited<\/a>\u00a0200+)<\/li>
  40. Liu, HF, Hsiao, PW, and Chao, JI* (2008<\/strong>) Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells.\u00a0Chemico-Biological Interactions<\/em><\/strong>, 176: 48-57.<\/li>
  41. Hsu, TS, Chen, C, Lee PT, Chiu, SJ, Liu, HF, and Chao, JI* (2008<\/strong>) 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound\u00a0 induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.\u00a0Cancer Chemotherapy and Pharmacology<\/em><\/strong>, 62: 799-808.\u00a0<\/li>
  42. Chang, CC*, Chen, PH, Chu, HL, Lee, TC, Chou, CC, Chao, JI, Su, JY, Chen, JS, Tsai, JS, Ho, YP, Sun, KW, and Cheng, CL (2008<\/strong>) Laser induced popcorn-like conformational transition of nanodiamond as a nano-knife.\u00a0Applied Physics Letters<\/em><\/strong>, 93: 3395.<\/li>
  43. Chiu, SJ*, Chao, JI, Lin, YJ, and Hsu, TS (2008<\/strong>) Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase -dependent pathway in human colorectal cancer cells.\u00a0Toxicology Letters<\/em><\/strong>, 179: 63-70.\u00a0<\/li>
  44. Liu, KK, Chen, MF, Chen, BI, Lee, TJF, Cheng, CL, Chang, CC, Ho, YP, and Chao, JI* (2008<\/strong>) Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond.\u00a0Nanotechnology<\/em><\/strong>, 19: 205102.\u00a0<\/li>
  45. Chiu, SJ, Hsu, TS, and Chao, JI* (2007<\/strong>) Expression of securin promotes colorectal cancer cell death via a p53-independent pathway after radiation.\u00a0Chemico-Biological Interactions<\/em><\/strong>, 170: 153\u2013161.\u00a0<\/li>
  46. Chao, JI*, Su, WC, and Liu, HF (2007<\/strong>) Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT.\u00a0Molecular Cancer Therapeutics<\/em><\/strong>, 6: 3039-3048.\u00a0(Times Cited<\/a>\u00a0160+)<\/li>
  47. Chao, JI, Perevedentseva, E, Chung, PH, Liu, KK, Cheng, CY, Chang, CC, and Cheng, CL* (2007<\/strong>) Nanometer-sized diamond particle as a probe for biolabeling.\u00a0Biophysical Journal<\/em><\/strong>, 93: 2199-2208#<\/sup>. (#<\/sup>Selected for the cover picture)(#<\/sup>Selected for the Virtual Journal of Nanotechnology Environment, Health and Safety, 2007)\u00a0(Times Cited<\/a>\u00a0290+)<\/li>
  48. Hsiao, PW, Chang, CC, Liu, HF, Tsai, CM, Chiu, TH, and Chao, JI* (2007<\/strong>) Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells.\u00a0Toxicology and Applied Pharmacology<\/em><\/strong>, 222: 97-104.<\/li>
  49. Liu, KK, Cheng, CL, Chang, CC and Chao, JI* (2007<\/strong>) Biocompatible and detectable carboxylated nanodiamond on human cell.\u00a0Nanotechnology<\/em><\/strong>, 18: 325102#<\/sup>. (#<\/sup>Selected for the Virtual Journal of Nanotechnology Environment, Health and Safety, 2007)(#<\/sup>Reported by the Nanotechnology Web of Nanowerk)\u00a0(Times Cited<\/a>\u00a0310+)<\/li>
  50. Cheng, CY, Perevedentseva, E, Tu, JS, Chung, PH, Cheng, CL*, Liu, KK, Chao, JI*, Chen, PH, Chang, CC* (2007<\/strong>) Direct and in vitro observation of growth hormone receptor molecules in A549 human lung epithelial cells by nanodiamond labeling.\u00a0Applied Physics Letters<\/em><\/strong>\u00a090: 163903#<\/sup>. (#<\/sup>Selected for the Virtual Journal of Biological Physics Research)\u00a0(Times <\/a>cited<\/a>\u00a0130+)<\/li>
  51. Chiu, SJ, Hsu, TS, and Chao, JI* (2006<\/strong>) Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells.\u00a0Toxicology Letters<\/em><\/strong>\u00a0167:122-130.\u00a0<\/li>
  52. Chao, JI*, Hsu, SH, and Tsou, TC (2006<\/strong>) Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway.\u00a0Toxicological Sciences<\/em><\/strong>\u00a090: 73-86.\u00a0<\/li>
  53. Chao, JI* and Liu, HF (2006<\/strong>) The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells.\u00a0Molecular Pharmacology<\/em><\/strong>\u00a069: 154-164.\u00a0<\/li>
  54. Hsu, SH, Tsou, TC, Chiu, SJ, and Chao, JI* (2005)<\/strong> Inhibition of \u03b17-nicotinic acetylcholine receptor expression by arsenite in the vascular endothelial cells.\u00a0Toxicology Letters<\/em><\/strong>\u00a0159: 47-59.\u00a0<\/li>
  55. Lin, J, Hsiao, PW, Chiu, TH, and Chao, JI* (2005<\/strong>) Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the cell death and growth inhibition in human colon cancer cells.\u00a0Biochemical Pharmacology<\/em><\/strong>\u00a070: 658\u2013667.<\/li>
  56. Kuo, PC, Liu, HF, and Chao, JI* (2004<\/strong>) Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells.\u00a0Journal of Biological Chemistry<\/em><\/strong>\u00a0279: 55875-55885.\u00a0(Times Cited<\/a>\u00a0180+)<\/li>
  57. Chao, JI*, Kuo, PC, and Hsu TS (2004<\/strong>) Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells.\u00a0Journal of Biological Chemistr<\/em>y<\/strong> 279: 20267-20276.\u00a0(Times cited<\/a>\u00a0130+)<\/mark><\/li><\/ol>\n\n\n\n

    BOOK CHAPTER<\/strong><\/h4>\n\n\n\n
    1. Chao, JI, Perevedentseva, E, Chang, CC, Cheng, CY, Liu, KK, Chung, PH, Tu, JS, Chu, CD, Cai, SJ, Cheng, CL (2010<\/strong>) Protein-nanodiamond complexes for cellular surgery, in nanodiamond and its bio applications using the spectroscopic properties as probe for bio-labeling. Nanodiamonds: Applications in Biology and Nanoscale Medicine<\/em><\/strong>, Springer, Chapter 9: 189-224.<\/li><\/ol>\n\n\n\n

      PATENTS<\/strong><\/h4>\n\n\n\n
      1. Chao,JI, Liu, KK, and Chen, CP. Quinazolinamine derivatives and pharmaceutical compositions and uses thereof<\/em> (Taiwan Patent <\/strong>Number: I660728; Patent Permission Date: 2019\/04\/12; Valid Dates: 2019\/06\/01-2038\/02\/08)<\/li>
      2. Chao,JI, Liu, KK, and Chen, CP. 4-anilinoquinazoline derivative and albumin conjugates thereof <\/em>(US Patent<\/strong> Number: US10251886 B1; Patent Permission Date: 2018\/12\/21; Valid Dates: 2019\/4\/9-2038\/02\/23)<\/li>
      3. Chao,JI, Liu, KK, and Hsu, YP. Method for overcoming drug resistance of EGFR mutation an cancerous stemness of human non-small cell lung carcinoma<\/em> (US Patent<\/strong> number: US9980967 B1; Patent Permission Date: 2018\/04\/05; Valid Dates: 2018\/05\/09-2037\/03\/16)<\/li>
      4. Chao,JI, Lien, ZY, and Hwang, KC. Separation method of labeled cells and uses thereof <\/em>(Taiwan Patent<\/strong> Number: I5888258; Valid Dates: 2017\/06\/21~2031\/11\/16)<\/li>
      5. Chao,JI, Lien, ZY, and Hwang, KC. Separation method of labeled cells and uses thereof<\/em> (US Patent<\/strong> Application No. 13\/471768; US Publication No. US 20130130236 A1).<\/li>
      6. Chao, JI, Wang, SP, Chen, C, Yin, KH, Yang, JM, and Wu, YH. A compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof<\/em> (People Republic of China Patent <\/strong>number: 2795573; Valid Dates: 2018\/01\/26~2034\/09\/22)<\/li>
      7. Chao, JI, Wang, SP, Chen, C, Yin, KH, Yang, JM, Wu, YH. A compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof<\/em> (Taiwan Patent<\/strong> Number: I567063; Valid Dates: 2017\/01\/21~2034\/09\/04)<\/li>
      8. Chao, JI, Wang, SP, Chen, C, Yin, KH, Yang, JM, and Wu, YH. A compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof<\/em> (US Patent<\/strong> Number: US9512086 B2; Valid Dates: 2016\/12\/6-2035\/1\/14)<\/li>
      9. Chao,JI, Yang, CR, and Chen, CP. A vitamin K3 derivative for promoting apoptosis: A pharmaceutical composition containing the same and a use thereof <\/em>(Taiwan Patent<\/strong> Number: I543759; Valid Dates: 2016\/08\/01~2034\/03\/10)<\/li>
      10. Yang, JM, Hsu, KC, Hwang, E, Chen, WL, Hwang, WJ, and Chao, JI. A specific inhibitor for epidermal growth factor Receptor, a pharmaceutical composition and an use thereof <\/em>(Taiwan Patent<\/strong> Number: I536987; Valid Dates: 2016\/06\/11~2033\/12\/26)<\/li>
      11. Chao, JI, Cheng, CL, and Chen, C. Medicine and carrier comprising nanodiamond, method for preparing the same and use thereof <\/em>(Taiwan Patent<\/strong> Number: I414309; Valid Dates: 2013\/11\/11~2029\/07\/12)<\/li>
      12. Chao, JI, Cheng, CL, and Chen, C. Medicine and carrier comprising nanodiamond, method for preparing the same and use thereof<\/em> (US Patent <\/strong>Application No. US 12\/574958; US Publication No. US 2011\/0008447 A1)<\/li>
      13. Chao, JI, Hsu, TS, Chen, C, Lee PT, and Chiu, SJ. Compound capable of cytoskeleton and induction of cell elongation and process for synthesizing the same <\/em>(Taiwan Patent<\/strong> Number: I359018; Valid Dates: 2012\/03\/01~2026\/07\/13).<\/li>
      14. Chao, JI, Hsu, TS, Chen, C, Lee PT, and Chiu, SJ. Compound capable of cytoskeleton and induction of cell elongation and process for synthesizing the same<\/em> (US Patent<\/strong> Publication No. US 2008\/0015221 A1)<\/li><\/ol>\n\n\n\n

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